Treprostinil

Common brands: Remodulin, Tyvaso, Letairis, Adcirca, Orenitram

Top reporter: United Therapeutics Corporation

Prostacycline Vasodilator [EPC]Endothelin Receptor Antagonist [EPC]Phosphodiesterase 5 Inhibitor [EPC]Loop Diuretic [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
121,654
Total Reports
57,011
Serious Reports
14,788
Death Reports
30
Reported Reactions
Death Report Ratio: High (12.16%)

Patient Demographics

Male
30,605
Female
87,442

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Treprostinil.

# Reaction Reports % of Total
1 DYSPNOEA 20,802
10.5%
2 HEADACHE 16,725
8.5%
3 DIARRHOEA 13,425
6.8%
4 NAUSEA 12,105
6.1%
5 COUGH 11,035
5.6%
6 DIZZINESS 9,164
4.6%
7 FATIGUE 9,102
4.6%
8 DEATH 8,879
4.5%
9 VOMITING 6,197
3.1%
10 INFUSION SITE PAIN 5,599
2.8%
11 HYPOTENSION 5,562
2.8%
12 PNEUMONIA 5,520
2.8%
13 MALAISE 5,493
2.8%
14 FLUID RETENTION 5,022
2.5%
15 PAIN IN EXTREMITY 4,830
2.4%
16 OXYGEN SATURATION DECREASED 4,747
2.4%
17 CHEST PAIN 4,540
2.3%
18 PAIN 4,461
2.3%
19 PULMONARY ARTERIAL HYPERTENSION 4,439
2.2%
20 OFF LABEL USE 4,358
2.2%
21 ASTHENIA 4,221
2.1%
22 DYSPNOEA EXERTIONAL 4,172
2.1%
23 FLUSHING 3,764
1.9%
24 WEIGHT DECREASED 3,727
1.9%
25 OEDEMA PERIPHERAL 3,536
1.8%
26 PAIN IN JAW 3,514
1.8%
27 DECREASED APPETITE 3,383
1.7%
28 INFUSION SITE ERYTHEMA 3,232
1.6%
29 FEELING ABNORMAL 3,143
1.6%
30 PERIPHERAL SWELLING 3,062
1.5%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.