Vismodegib

Common brands: Erivedge, Zestril, Lisinopril, Qbrelis, Aspirin 325

Top reporter: Genentech, Inc.

Hedgehog Pathway Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]HMG-CoA Reductase Inhibitor [EPC]Platelet Aggregation Inhibitor [EPC]Loop Diuretic [EPC]
8,768
Total Reports
2,913
Serious Reports
976
Death Reports
30
Reported Reactions
Death Report Ratio: High (11.13%)

Patient Demographics

Male
4,897
Female
3,218

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Vismodegib.

# Reaction Reports % of Total
1 MUSCLE SPASMS 2,042
15.0%
2 ALOPECIA 1,392
10.3%
3 AGEUSIA 1,002
7.4%
4 FATIGUE 961
7.1%
5 DYSGEUSIA 745
5.5%
6 DEATH 740
5.5%
7 WEIGHT DECREASED 732
5.4%
8 NAUSEA 706
5.2%
9 DECREASED APPETITE 700
5.2%
10 DIARRHOEA 470
3.5%
11 CONSTIPATION 378
2.8%
12 OFF LABEL USE 369
2.7%
13 ASTHENIA 292
2.2%
14 ARTHRALGIA 279
2.1%
15 NO ADVERSE EVENT 257
1.9%
16 VOMITING 257
1.9%
17 PAIN 245
1.8%
18 TASTE DISORDER 236
1.7%
19 MYALGIA 213
1.6%
20 DRUG INEFFECTIVE 194
1.4%
21 HEADACHE 182
1.3%
22 MALAISE 160
1.2%
23 FALL 139
1.0%
24 RASH 138
1.0%
25 BASAL CELL CARCINOMA 137
1.0%
26 DEHYDRATION 130
1.0%
27 DIZZINESS 130
1.0%
28 ABDOMINAL PAIN UPPER 119
0.9%
29 DYSPNOEA 114
0.8%
30 SQUAMOUS CELL CARCINOMA 111
0.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.