Avapritinib

Common brands: Ayvakit, Acid Reducer, Pepcid, Acid Controller, Basic Care Acid Reducer

Top reporter: Blueprint Medicines Corporation

Kinase Inhibitor [EPC]Histamine-2 Receptor Antagonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Serotonin-3 Receptor Antagonist [EPC]Provitamin D2 Compound [EPC]
11,414
Total Reports
10,180
Serious Reports
345
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (3.02%)

Patient Demographics

Male
4,594
Female
6,252

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Avapritinib.

# Reaction Reports % of Total
1 FATIGUE 1,651
10.8%
2 OFF LABEL USE 1,284
8.4%
3 NAUSEA 1,168
7.6%
4 DIARRHOEA 974
6.4%
5 HEADACHE 531
3.5%
6 DIZZINESS 509
3.3%
7 SWELLING FACE 508
3.3%
8 MEMORY IMPAIRMENT 503
3.3%
9 VOMITING 500
3.3%
10 ASTHENIA 456
3.0%
11 PERIPHERAL SWELLING 447
2.9%
12 RASH 446
2.9%
13 PLATELET COUNT DECREASED 443
2.9%
14 PRODUCT DOSE OMISSION ISSUE 435
2.8%
15 LACRIMATION INCREASED 425
2.8%
16 DECREASED APPETITE 411
2.7%
17 PERIORBITAL SWELLING 394
2.6%
18 EYE SWELLING 387
2.5%
19 PAIN 381
2.5%
20 INSOMNIA 374
2.4%
21 HAIR COLOUR CHANGES 364
2.4%
22 DRUG INEFFECTIVE 333
2.2%
23 MALAISE 326
2.1%
24 FEELING ABNORMAL 304
2.0%
25 PRURITUS 295
1.9%
26 ARTHRALGIA 291
1.9%
27 ABDOMINAL PAIN UPPER 290
1.9%
28 BRAIN FOG 289
1.9%
29 HAEMOGLOBIN DECREASED 280
1.8%
30 ALOPECIA 273
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.