Cabozantinib

Common brands: Cabometyx, Opdivo, Cometriq, Katerzia, Norliqva

Top reporter: Exelixis, Inc.

Programmed Death Receptor-1 Blocking Antibody [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Corticosteroid [EPC]Dihydropyridine Calcium Channel Blocker [EPC]Calcium Channel Blocker [EPC]
46,986
Total Reports
32,516
Serious Reports
5,140
Death Reports
30
Reported Reactions
Death Report Ratio: High (10.94%)

Patient Demographics

Male
30,801
Female
12,953

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Cabozantinib.

# Reaction Reports % of Total
1 DIARRHOEA 9,366
11.4%
2 FATIGUE 7,628
9.3%
3 OFF LABEL USE 6,782
8.2%
4 NAUSEA 4,944
6.0%
5 DECREASED APPETITE 4,579
5.6%
6 MALIGNANT NEOPLASM PROGRESSION 3,344
4.1%
7 BLOOD PRESSURE INCREASED 3,177
3.9%
8 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 3,079
3.7%
9 WEIGHT DECREASED 3,002
3.7%
10 STOMATITIS 2,875
3.5%
11 DEATH 2,781
3.4%
12 CONSTIPATION 2,352
2.9%
13 VOMITING 2,198
2.7%
14 ASTHENIA 2,124
2.6%
15 BLISTER 2,089
2.5%
16 TASTE DISORDER 1,981
2.4%
17 HYPERTENSION 1,861
2.3%
18 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 1,846
2.2%
19 RASH 1,805
2.2%
20 PAIN IN EXTREMITY 1,776
2.2%
21 MALAISE 1,775
2.2%
22 DYSPHONIA 1,391
1.7%
23 ADVERSE DRUG REACTION 1,350
1.6%
24 DRY SKIN 1,298
1.6%
25 PAIN 1,220
1.5%
26 PRURITUS 1,192
1.4%
27 ORAL PAIN 1,187
1.4%
28 SKIN ULCER 1,129
1.4%
29 HEADACHE 1,074
1.3%
30 DIZZINESS 1,033
1.3%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.