Diphenoxylate Hydrochloride / Atropine Sulfate

Common brands: Lomotil, Vitamin D, Neurontin, Ecotrin, Aspirin 325

Top reporter: Pfizer Laboratories Div Pfizer Inc

Benzodiazepine [EPC]Corticosteroid [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Provitamin D2 Compound [EPC]Platelet Aggregation Inhibitor [EPC]
13,472
Total Reports
3,876
Serious Reports
1,328
Death Reports
30
Reported Reactions
Death Report Ratio: High (9.86%)

Patient Demographics

Male
4,647
Female
8,187

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Diphenoxylate Hydrochloride / Atropine Sulfate.

# Reaction Reports % of Total
1 DIARRHOEA 2,697
12.5%
2 NAUSEA 1,595
7.4%
3 FATIGUE 1,452
6.7%
4 DRUG INEFFECTIVE 1,119
5.2%
5 VOMITING 908
4.2%
6 WEIGHT DECREASED 868
4.0%
7 PAIN 777
3.6%
8 DEHYDRATION 761
3.5%
9 OFF LABEL USE 740
3.4%
10 ABDOMINAL PAIN 734
3.4%
11 ASTHENIA 707
3.3%
12 HEADACHE 662
3.1%
13 DYSPNOEA 660
3.1%
14 DECREASED APPETITE 637
3.0%
15 MALAISE 588
2.7%
16 PYREXIA 576
2.7%
17 DEATH 551
2.6%
18 PNEUMONIA 527
2.4%
19 DIZZINESS 523
2.4%
20 ARTHRALGIA 514
2.4%
21 CONSTIPATION 498
2.3%
22 FALL 468
2.2%
23 ANAEMIA 461
2.1%
24 RASH 412
1.9%
25 URINARY TRACT INFECTION 395
1.8%
26 PAIN IN EXTREMITY 368
1.7%
27 BACK PAIN 363
1.7%
28 COUGH 352
1.6%
29 CROHN^S DISEASE 348
1.6%
30 HYPOTENSION 315
1.5%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.