Epoprostenol

Common brands: Veletri, Letairis, Adcirca, Opsumit, Sildenafil

Top reporter: Actelion Pharmaceuticals Us, Inc.

Prostacycline Vasodilator [EPC]Endothelin Receptor Antagonist [EPC]Phosphodiesterase 5 Inhibitor [EPC]Loop Diuretic [EPC]Soluble Guanylate Cyclase Stimulator [EPC]
12,893
Total Reports
4,621
Serious Reports
2,665
Death Reports
30
Reported Reactions
Death Report Ratio: High (20.67%)

Patient Demographics

Male
2,884
Female
9,489

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Epoprostenol.

# Reaction Reports % of Total
1 DYSPNOEA 2,765
8.9%
2 HEADACHE 2,280
7.4%
3 DIARRHOEA 2,159
7.0%
4 NAUSEA 1,950
6.3%
5 PAIN IN JAW 1,846
6.0%
6 DEATH 1,324
4.3%
7 FLUSHING 1,166
3.8%
8 PULMONARY ARTERIAL HYPERTENSION 1,106
3.6%
9 FATIGUE 1,101
3.6%
10 VOMITING 1,041
3.4%
11 DYSPNOEA EXERTIONAL 962
3.1%
12 FLUID RETENTION 924
3.0%
13 MALAISE 886
2.9%
14 PNEUMONIA 881
2.8%
15 PAIN IN EXTREMITY 845
2.7%
16 DIZZINESS 824
2.7%
17 HYPOTENSION 802
2.6%
18 CONDITION AGGRAVATED 797
2.6%
19 CHEST PAIN 718
2.3%
20 WEIGHT DECREASED 685
2.2%
21 HOSPITALISATION 655
2.1%
22 PAIN 651
2.1%
23 DEVICE RELATED INFECTION 641
2.1%
24 COUGH 579
1.9%
25 PALPITATIONS 570
1.8%
26 PULMONARY HYPERTENSION 569
1.8%
27 ASTHENIA 563
1.8%
28 CATHETER SITE ERYTHEMA 562
1.8%
29 PYREXIA 556
1.8%
30 RASH 556
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.