Etanercept

Common brands: Enbrel, Methotrexate, Trexall, Rasuvo, Otrexup

Top reporter: Immunex Corporation

Tumor Necrosis Factor Blocker [EPC]Folate Analog Metabolic Inhibitor [EPC]Corticosteroid [EPC]Antirheumatic Agent [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
592,886
Total Reports
68,976
Serious Reports
16,796
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (2.83%)

Patient Demographics

Male
139,296
Female
408,598

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Etanercept.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 75,212
9.7%
2 INJECTION SITE PAIN 56,701
7.3%
3 RHEUMATOID ARTHRITIS 46,370
6.0%
4 ARTHRALGIA 45,138
5.8%
5 PAIN 43,199
5.6%
6 INJECTION SITE ERYTHEMA 41,025
5.3%
7 FATIGUE 30,416
3.9%
8 JOINT SWELLING 25,549
3.3%
9 PAIN IN EXTREMITY 25,531
3.3%
10 PSORIASIS 25,033
3.2%
11 HEADACHE 24,800
3.2%
12 INJECTION SITE SWELLING 23,263
3.0%
13 OFF LABEL USE 22,314
2.9%
14 INJECTION SITE PRURITUS 22,094
2.9%
15 INJECTION SITE REACTION 20,885
2.7%
16 NASOPHARYNGITIS 20,724
2.7%
17 CONDITION AGGRAVATED 20,646
2.7%
18 RASH 20,202
2.6%
19 NAUSEA 19,316
2.5%
20 MALAISE 18,718
2.4%
21 DRUG INTOLERANCE 16,729
2.2%
22 SINUSITIS 16,544
2.1%
23 DRUG HYPERSENSITIVITY 14,909
1.9%
24 MUSCULOSKELETAL STIFFNESS 14,554
1.9%
25 ARTHROPATHY 14,425
1.9%
26 ALOPECIA 14,354
1.9%
27 PERIPHERAL SWELLING 14,229
1.8%
28 HYPERSENSITIVITY 14,015
1.8%
29 INJECTION SITE BRUISING 13,738
1.8%
30 DIARRHOEA 13,713
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.