Isoniazid

Common brands: Pyrazinamide, Rifadin Iv, Rifampin, Levofloxacin, Methotrexate

Top reporter: Cmp Pharma, Inc.

Antimycobacterial [EPC]Rifamycin Antibacterial [EPC]Corticosteroid [EPC]Fluoroquinolone Antibacterial [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
15,899
Total Reports
6,065
Serious Reports
2,168
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.64%)

Patient Demographics

Male
7,046
Female
6,933

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Isoniazid.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 1,166
6.9%
2 PYREXIA 1,096
6.5%
3 DRUG INTERACTION 919
5.4%
4 NAUSEA 897
5.3%
5 DRUG-INDUCED LIVER INJURY 850
5.0%
6 OFF LABEL USE 832
4.9%
7 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 733
4.3%
8 VOMITING 631
3.7%
9 HEADACHE 613
3.6%
10 PARADOXICAL DRUG REACTION 551
3.3%
11 ARTHRALGIA 544
3.2%
12 TUBERCULOSIS 539
3.2%
13 DIARRHOEA 503
3.0%
14 RASH 501
3.0%
15 CONDITION AGGRAVATED 495
2.9%
16 HEPATOTOXICITY 493
2.9%
17 DYSPNOEA 488
2.9%
18 ANAEMIA 475
2.8%
19 MALAISE 466
2.8%
20 DRUG RESISTANCE 454
2.7%
21 FATIGUE 416
2.5%
22 PAIN 397
2.4%
23 JAUNDICE 385
2.3%
24 COUGH 364
2.2%
25 HEPATITIS 359
2.1%
26 ABDOMINAL PAIN 358
2.1%
27 PNEUMONIA 351
2.1%
28 ALANINE AMINOTRANSFERASE INCREASED 336
2.0%
29 WEIGHT DECREASED 329
2.0%
30 TOXICITY TO VARIOUS AGENTS 322
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.