Lamotirigine

Common brands: Lamictal, Lamictal Odt, Lamictal Xr, Lamotrigine, Lamotrigine Extended-Release

Top reporter: Actavis Pharma, Inc.

Anti-epileptic Agent [EPC]Mood Stabilizer [EPC]Benzodiazepine [EPC]Atypical Antipsychotic [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
69,811
Total Reports
29,559
Serious Reports
8,021
Death Reports
30
Reported Reactions
Death Report Ratio: High (11.49%)

Patient Demographics

Male
20,006
Female
39,131

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Lamotirigine.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 6,074
8.2%
2 SEIZURE 4,209
5.7%
3 TOXICITY TO VARIOUS AGENTS 3,875
5.3%
4 OFF LABEL USE 3,359
4.6%
5 DRUG INTERACTION 3,160
4.3%
6 COMPLETED SUICIDE 3,063
4.2%
7 FATIGUE 2,903
3.9%
8 NAUSEA 2,894
3.9%
9 DIZZINESS 2,889
3.9%
10 RASH 2,796
3.8%
11 FOETAL EXPOSURE DURING PREGNANCY 2,680
3.6%
12 HEADACHE 2,624
3.6%
13 SOMNOLENCE 2,500
3.4%
14 DEPRESSION 2,334
3.2%
15 VOMITING 2,243
3.0%
16 CONDITION AGGRAVATED 2,186
3.0%
17 ANXIETY 2,097
2.8%
18 PYREXIA 1,989
2.7%
19 EPILEPSY 1,827
2.5%
20 FALL 1,825
2.5%
21 INTENTIONAL OVERDOSE 1,772
2.4%
22 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 1,746
2.4%
23 CONFUSIONAL STATE 1,651
2.2%
24 TREMOR 1,644
2.2%
25 OVERDOSE 1,638
2.2%
26 MATERNAL EXPOSURE DURING PREGNANCY 1,583
2.1%
27 INSOMNIA 1,569
2.1%
28 DIARRHOEA 1,566
2.1%
29 PAIN 1,517
2.1%
30 CONVULSION 1,471
2.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.