Lubiprostone

Common brands: Amitiza, Vitamin D, Neurontin, Acid Reducer, Lasix

Top reporter: Specgx Llc

Chloride Channel Activator [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Benzodiazepine [EPC]Proton Pump Inhibitor [EPC]Corticosteroid [EPC]
9,235
Total Reports
2,874
Serious Reports
945
Death Reports
30
Reported Reactions
Death Report Ratio: High (10.23%)

Patient Demographics

Male
2,575
Female
5,983

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Lubiprostone.

# Reaction Reports % of Total
1 NAUSEA 777
7.2%
2 DYSPNOEA 628
5.8%
3 DIARRHOEA 593
5.5%
4 CONSTIPATION 573
5.3%
5 DRUG INEFFECTIVE 553
5.1%
6 FATIGUE 526
4.8%
7 PAIN 491
4.5%
8 HEADACHE 487
4.5%
9 DIZZINESS 446
4.1%
10 FALL 403
3.7%
11 VOMITING 389
3.6%
12 CHRONIC KIDNEY DISEASE 334
3.1%
13 OFF LABEL USE 330
3.0%
14 MALAISE 315
2.9%
15 PYREXIA 298
2.7%
16 ASTHENIA 285
2.6%
17 PNEUMONIA 280
2.6%
18 ANXIETY 276
2.5%
19 DECREASED APPETITE 268
2.5%
20 RENAL FAILURE 260
2.4%
21 DEPRESSION 257
2.4%
22 WEIGHT DECREASED 257
2.4%
23 ABDOMINAL PAIN 250
2.3%
24 ACUTE KIDNEY INJURY 243
2.2%
25 DEATH 239
2.2%
26 INSOMNIA 239
2.2%
27 ARTHRALGIA 234
2.2%
28 RASH 216
2.0%
29 CHEST PAIN 209
1.9%
30 FEELING ABNORMAL 208
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.