Metformin

Common brands: Metformin Hydrochloride, Glumetza, Riomet, Metformin Hydrochloride Er, Metformin Hydrochloride Extended Release

Top reporter: Granules Pharmaceuticals Inc.

Nonsteroidal Anti-inflammatory Drug [EPC]Insulin Analog [EPC]HMG-CoA Reductase Inhibitor [EPC]Platelet Aggregation Inhibitor [EPC]GLP-1 Receptor Agonist [EPC]
348,087
Total Reports
129,185
Serious Reports
29,280
Death Reports
30
Reported Reactions
Death Report Ratio: High (8.41%)

Patient Demographics

Male
147,287
Female
171,865

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Metformin.

# Reaction Reports % of Total
1 NAUSEA 22,422
6.4%
2 DIARRHOEA 22,388
6.4%
3 DRUG INEFFECTIVE 18,568
5.3%
4 BLOOD GLUCOSE INCREASED 18,470
5.3%
5 FATIGUE 17,569
5.0%
6 ACUTE KIDNEY INJURY 16,774
4.8%
7 LACTIC ACIDOSIS 16,554
4.7%
8 VOMITING 15,128
4.3%
9 DYSPNOEA 13,753
3.9%
10 OFF LABEL USE 13,656
3.9%
11 DIZZINESS 12,375
3.5%
12 HEADACHE 12,167
3.5%
13 WEIGHT DECREASED 12,130
3.5%
14 PAIN 11,786
3.4%
15 ASTHENIA 10,655
3.0%
16 MALAISE 10,528
3.0%
17 FALL 9,547
2.7%
18 ARTHRALGIA 9,012
2.6%
19 DECREASED APPETITE 8,869
2.5%
20 DEATH 7,777
2.2%
21 PAIN IN EXTREMITY 7,706
2.2%
22 PNEUMONIA 7,485
2.1%
23 COUGH 7,199
2.1%
24 HYPOGLYCAEMIA 7,100
2.0%
25 PRURITUS 7,081
2.0%
26 TOXICITY TO VARIOUS AGENTS 7,031
2.0%
27 RASH 6,999
2.0%
28 ABDOMINAL PAIN 6,981
2.0%
29 HYPOTENSION 6,846
1.9%
30 INJECTION SITE PAIN 6,539
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.