Modafinil

Common brands: Provigil, Xyrem, Vitamin D, Neurontin, Gralise

Top reporter: Apotex Corp

Sympathomimetic-like Agent [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Benzodiazepine [EPC]Provitamin D2 Compound [EPC]Corticosteroid [EPC]
31,875
Total Reports
7,298
Serious Reports
1,064
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (3.34%)

Patient Demographics

Male
9,306
Female
21,447

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Modafinil.

# Reaction Reports % of Total
1 FATIGUE 2,925
8.0%
2 NAUSEA 2,234
6.1%
3 DRUG INEFFECTIVE 2,123
5.8%
4 HEADACHE 1,855
5.1%
5 FALL 1,778
4.9%
6 DEPRESSION 1,606
4.4%
7 ANXIETY 1,493
4.1%
8 SOMNOLENCE 1,404
3.9%
9 DIZZINESS 1,397
3.8%
10 PAIN 1,284
3.5%
11 INSOMNIA 1,141
3.1%
12 CONDITION AGGRAVATED 1,129
3.1%
13 FEELING ABNORMAL 1,113
3.1%
14 WEIGHT DECREASED 1,102
3.0%
15 ASTHENIA 1,072
2.9%
16 VOMITING 1,031
2.8%
17 DIARRHOEA 977
2.7%
18 DYSPNOEA 953
2.6%
19 GAIT DISTURBANCE 947
2.6%
20 OFF LABEL USE 903
2.5%
21 HYPERTENSION 891
2.4%
22 MALAISE 890
2.4%
23 MULTIPLE SCLEROSIS RELAPSE 865
2.4%
24 MEMORY IMPAIRMENT 833
2.3%
25 SLEEP APNOEA SYNDROME 773
2.1%
26 URINARY TRACT INFECTION 760
2.1%
27 MUSCLE SPASMS 757
2.1%
28 TREMOR 736
2.0%
29 ARTHRALGIA 735
2.0%
30 MULTIPLE SCLEROSIS 686
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.