Pazopanib

Common brands: Votrient, Pazopanib, Katerzia, Norliqva, Sdamlo

Top reporter: Novartis Pharmaceuticals Corporation

Kinase Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Dihydropyridine Calcium Channel Blocker [EPC]Benzodiazepine [EPC]Corticosteroid [EPC]
26,802
Total Reports
9,251
Serious Reports
6,927
Death Reports
30
Reported Reactions
Death Report Ratio: High (25.85%)

Patient Demographics

Male
14,010
Female
9,847

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Pazopanib.

# Reaction Reports % of Total
1 DEATH 4,574
13.6%
2 DIARRHOEA 3,596
10.7%
3 FATIGUE 2,484
7.4%
4 NAUSEA 2,418
7.2%
5 MALIGNANT NEOPLASM PROGRESSION 1,656
4.9%
6 DRUG INEFFECTIVE 1,469
4.4%
7 DECREASED APPETITE 1,436
4.3%
8 VOMITING 1,403
4.2%
9 HYPERTENSION 1,253
3.7%
10 DISEASE PROGRESSION 1,008
3.0%
11 ASTHENIA 931
2.8%
12 MALAISE 900
2.7%
13 WEIGHT DECREASED 882
2.6%
14 DYSPNOEA 842
2.5%
15 HAIR COLOUR CHANGES 831
2.5%
16 BLOOD PRESSURE INCREASED 785
2.3%
17 PRODUCT USE IN UNAPPROVED INDICATION 762
2.3%
18 HEADACHE 716
2.1%
19 PAIN 671
2.0%
20 ABDOMINAL PAIN 516
1.5%
21 PYREXIA 505
1.5%
22 DYSGEUSIA 504
1.5%
23 RASH 498
1.5%
24 ABDOMINAL PAIN UPPER 490
1.5%
25 OFF LABEL USE 449
1.3%
26 ABDOMINAL DISCOMFORT 418
1.2%
27 DIZZINESS 416
1.2%
28 PAIN IN EXTREMITY 415
1.2%
29 DEHYDRATION 401
1.2%
30 HEPATIC ENZYME INCREASED 389
1.2%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.