Selinexor

Common brands: Xpovio, Hemady, Dexamethasone, Dexamethasone 1.5 Mg, Dextenza

Top reporter: Karyopharm Therapeutics Inc.

Nuclear Export Inhibitor [EPC]Corticosteroid [EPC]Proteasome Inhibitor [EPC]Serotonin-3 Receptor Antagonist [EPC]Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
8,359
Total Reports
6,007
Serious Reports
1,412
Death Reports
30
Reported Reactions
Death Report Ratio: High (16.89%)

Patient Demographics

Male
1,604
Female
1,340

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Selinexor.

# Reaction Reports % of Total
1 NAUSEA 2,559
13.6%
2 FATIGUE 1,937
10.3%
3 DECREASED APPETITE 1,367
7.2%
4 DIARRHOEA 1,288
6.8%
5 PLASMA CELL MYELOMA 1,157
6.1%
6 VOMITING 928
4.9%
7 ASTHENIA 850
4.5%
8 DEATH 832
4.4%
9 THROMBOCYTOPENIA 735
3.9%
10 PLATELET COUNT DECREASED 663
3.5%
11 WEIGHT DECREASED 637
3.4%
12 OFF LABEL USE 504
2.7%
13 PNEUMONIA 464
2.5%
14 ANAEMIA 463
2.5%
15 DIZZINESS 450
2.4%
16 CONSTIPATION 436
2.3%
17 DRUG INEFFECTIVE 416
2.2%
18 WHITE BLOOD CELL COUNT DECREASED 310
1.6%
19 DYSPNOEA 301
1.6%
20 FALL 283
1.5%
21 DEHYDRATION 279
1.5%
22 PYREXIA 251
1.3%
23 NEUTROPENIA 242
1.3%
24 PRODUCT DOSE OMISSION ISSUE 237
1.3%
25 HEADACHE 233
1.2%
26 CONFUSIONAL STATE 231
1.2%
27 HYPONATRAEMIA 216
1.1%
28 HAEMOGLOBIN DECREASED 210
1.1%
29 INSOMNIA 192
1.0%
30 SOMNOLENCE 192
1.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.