Spironolactone

Common brands: Aldactone, Lasix, Furosemide, Lasix Onyu, Aspirin 325

Top reporter: Pfizer Laboratories Div Pfizer Inc

Aldosterone Antagonist [EPC]Loop Diuretic [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Proton Pump Inhibitor [EPC]Corticosteroid [EPC]
136,771
Total Reports
58,783
Serious Reports
17,853
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.05%)

Patient Demographics

Male
52,467
Female
74,924

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Spironolactone.

# Reaction Reports % of Total
1 DYSPNOEA 10,607
6.9%
2 FATIGUE 8,370
5.5%
3 NAUSEA 7,992
5.2%
4 DIARRHOEA 7,587
4.9%
5 ACUTE KIDNEY INJURY 6,899
4.5%
6 DIZZINESS 6,378
4.2%
7 HEADACHE 6,027
3.9%
8 HYPOTENSION 5,906
3.8%
9 OFF LABEL USE 5,769
3.8%
10 DRUG INEFFECTIVE 5,306
3.5%
11 FALL 5,168
3.4%
12 ASTHENIA 5,091
3.3%
13 DEATH 4,996
3.3%
14 HYPERKALAEMIA 4,986
3.2%
15 VOMITING 4,955
3.2%
16 CARDIAC FAILURE 4,540
3.0%
17 PNEUMONIA 4,491
2.9%
18 MALAISE 4,478
2.9%
19 PAIN 4,437
2.9%
20 COUGH 4,120
2.7%
21 DRUG INTERACTION 3,910
2.5%
22 ANAEMIA 3,850
2.5%
23 OEDEMA PERIPHERAL 3,755
2.4%
24 WEIGHT DECREASED 3,736
2.4%
25 RENAL FAILURE 3,683
2.4%
26 CONDITION AGGRAVATED 3,510
2.3%
27 DEHYDRATION 3,379
2.2%
28 ARTHRALGIA 3,284
2.1%
29 DECREASED APPETITE 3,189
2.1%
30 CARDIAC FAILURE CONGESTIVE 3,071
2.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.