Tiotropium Bromide

Common brands: Spiriva Handihaler, Albuterol, Symbicort, Ventolin Hfa, Prednisone

Top reporter: Boehringer Ingelheim Pharmaceuticals, Inc.

Corticosteroid [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Loop Diuretic [EPC]Benzodiazepine [EPC]Platelet Aggregation Inhibitor [EPC]
135,600
Total Reports
25,255
Serious Reports
9,762
Death Reports
30
Reported Reactions
Death Report Ratio: High (7.20%)

Patient Demographics

Male
49,919
Female
76,581

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Tiotropium Bromide.

# Reaction Reports % of Total
1 INCORRECT ROUTE OF DRUG ADMINISTRATION 23,320
13.2%
2 DYSPNOEA 22,482
12.7%
3 ASTHMA 10,939
6.2%
4 DRUG INEFFECTIVE 9,428
5.3%
5 COUGH 8,694
4.9%
6 PNEUMONIA 8,441
4.8%
7 WHEEZING 6,850
3.9%
8 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 6,268
3.5%
9 PRODUCT QUALITY ISSUE 5,974
3.4%
10 FATIGUE 5,397
3.0%
11 OFF LABEL USE 4,722
2.7%
12 MALAISE 4,564
2.6%
13 NAUSEA 4,052
2.3%
14 FALL 3,944
2.2%
15 HEADACHE 3,892
2.2%
16 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 3,847
2.2%
17 DEATH 3,818
2.2%
18 PRODUCTIVE COUGH 3,698
2.1%
19 DIZZINESS 3,649
2.1%
20 PAIN 3,451
1.9%
21 DIARRHOEA 3,339
1.9%
22 ASTHENIA 3,316
1.9%
23 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 3,262
1.8%
24 CHEST DISCOMFORT 3,198
1.8%
25 WEIGHT DECREASED 3,089
1.7%
26 OBSTRUCTIVE AIRWAYS DISORDER 2,802
1.6%
27 NASOPHARYNGITIS 2,715
1.5%
28 VOMITING 2,665
1.5%
29 BRONCHITIS 2,621
1.5%
30 DRY MOUTH 2,556
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.