Topiramate

Common brands: Topamax, Trokendi Xr, Qudexy Xr, Eprontia, Neurontin

Top reporter: Janssen Pharmaceuticals, Inc.

Benzodiazepine [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Anti-epileptic Agent [EPC]Mood Stabilizer [EPC]Corticosteroid [EPC]
91,332
Total Reports
28,752
Serious Reports
6,662
Death Reports
30
Reported Reactions
Death Report Ratio: High (7.29%)

Patient Demographics

Male
17,869
Female
63,730

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Topiramate.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 10,293
9.2%
2 OFF LABEL USE 7,397
6.6%
3 HEADACHE 6,554
5.8%
4 NAUSEA 5,841
5.2%
5 FATIGUE 5,383
4.8%
6 PAIN 4,558
4.1%
7 MIGRAINE 4,451
4.0%
8 DIZZINESS 4,201
3.7%
9 SEIZURE 3,831
3.4%
10 DIARRHOEA 3,684
3.3%
11 VOMITING 3,629
3.2%
12 DEPRESSION 3,603
3.2%
13 PRODUCT USE IN UNAPPROVED INDICATION 3,130
2.8%
14 WEIGHT INCREASED 3,004
2.7%
15 WEIGHT DECREASED 2,999
2.7%
16 DYSPNOEA 2,934
2.6%
17 PARAESTHESIA 2,922
2.6%
18 CONDITION AGGRAVATED 2,896
2.6%
19 FALL 2,877
2.6%
20 SOMNOLENCE 2,786
2.5%
21 INSOMNIA 2,768
2.5%
22 ANXIETY 2,748
2.5%
23 MALAISE 2,609
2.3%
24 RASH 2,607
2.3%
25 MEMORY IMPAIRMENT 2,542
2.3%
26 ARTHRALGIA 2,535
2.3%
27 ASTHENIA 2,391
2.1%
28 HYPOAESTHESIA 2,362
2.1%
29 DRUG INTOLERANCE 2,296
2.0%
30 CONFUSIONAL STATE 2,269
2.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.