Trifluridine / Tipiracil

Common brands: Lonsurf, Avastin, Ondansetron, Neurontin, Gaba 300-Ezs

Top reporter: Taiho Pharmaceutical Co., Ltd.

Nucleoside Analog Antiviral [EPC]Nucleoside Metabolic Inhibitor [EPC]Vascular Endothelial Growth Factor Inhibitor [EPC]Opioid Agonist [EPC]Benzodiazepine [EPC]
10,494
Total Reports
5,148
Serious Reports
4,196
Death Reports
30
Reported Reactions
Death Report Ratio: High (39.98%)

Patient Demographics

Male
5,957
Female
4,318

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Trifluridine / Tipiracil.

# Reaction Reports % of Total
1 DEATH 3,079
19.1%
2 DISEASE PROGRESSION 1,795
11.1%
3 FATIGUE 1,371
8.5%
4 NAUSEA 1,150
7.1%
5 DIARRHOEA 987
6.1%
6 DECREASED APPETITE 679
4.2%
7 VOMITING 617
3.8%
8 ASTHENIA 485
3.0%
9 WHITE BLOOD CELL COUNT DECREASED 482
3.0%
10 DRUG INEFFECTIVE 360
2.2%
11 ANAEMIA 352
2.2%
12 WEIGHT DECREASED 329
2.0%
13 CONSTIPATION 327
2.0%
14 NEUTROPENIA 322
2.0%
15 DEHYDRATION 320
2.0%
16 OFF LABEL USE 314
1.9%
17 ABDOMINAL PAIN 312
1.9%
18 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 306
1.9%
19 PAIN 264
1.6%
20 MALAISE 260
1.6%
21 ABDOMINAL PAIN UPPER 250
1.5%
22 PYREXIA 250
1.5%
23 PLATELET COUNT DECREASED 230
1.4%
24 MALIGNANT NEOPLASM PROGRESSION 227
1.4%
25 DYSPNOEA 215
1.3%
26 HAEMOGLOBIN DECREASED 182
1.1%
27 ALOPECIA 175
1.1%
28 DIZZINESS 174
1.1%
29 CYTOPENIA 173
1.1%
30 URINARY TRACT INFECTION 165
1.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.