Ibuprofen / Diphenhydramine Citrate

Common brands: Motrin Pm, Motrin Infants, Advil Pm, Advil Pm- Diphenhydramine Citrate And Ibuprofen Tablet, Coated, Tylenol Extra Strength

Top reporter: Kenvue Brands Llc

Nonsteroidal Anti-inflammatory Drug [EPC]Benzodiazepine [EPC]Expectorant [EPC]Corticosteroid [EPC]Platelet Aggregation Inhibitor [EPC]
23,036
Total Reports
3,945
Serious Reports
798
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (3.46%)

Patient Demographics

Male
5,832
Female
14,801

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Ibuprofen / Diphenhydramine Citrate.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 2,808
9.7%
2 PAIN 1,950
6.7%
3 NAUSEA 1,788
6.2%
4 HEADACHE 1,722
6.0%
5 FATIGUE 1,413
4.9%
6 DIZZINESS 1,216
4.2%
7 VOMITING 1,084
3.8%
8 ANXIETY 1,068
3.7%
9 DRUG HYPERSENSITIVITY 1,043
3.6%
10 DIARRHOEA 927
3.2%
11 ARTHRALGIA 882
3.1%
12 DYSPNOEA 880
3.0%
13 INSOMNIA 833
2.9%
14 OFF LABEL USE 815
2.8%
15 PAIN IN EXTREMITY 756
2.6%
16 SOMNOLENCE 756
2.6%
17 INJURY 706
2.4%
18 DEPRESSION 705
2.4%
19 ABDOMINAL DISCOMFORT 673
2.3%
20 FEELING ABNORMAL 665
2.3%
21 BACK PAIN 657
2.3%
22 ABDOMINAL PAIN UPPER 652
2.3%
23 RASH 648
2.2%
24 WEIGHT DECREASED 629
2.2%
25 MALAISE 625
2.2%
26 ASTHENIA 612
2.1%
27 PYREXIA 611
2.1%
28 ABDOMINAL PAIN 598
2.1%
29 PULMONARY EMBOLISM 588
2.0%
30 DECREASED APPETITE 586
2.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.