Lamotrigine

Common brands: Lamictal Xr, Lamictal Odt, Lamictal, Subvenite, Lamotrigine Extended-Release

Top reporter: Glaxosmithkline Llc

Anti-epileptic Agent [EPC]Mood Stabilizer [EPC]Benzodiazepine [EPC]Atypical Antipsychotic [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
129,125
Total Reports
40,388
Serious Reports
11,033
Death Reports
30
Reported Reactions
Death Report Ratio: High (8.54%)

Patient Demographics

Male
35,579
Female
76,489

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Lamotrigine.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 10,083
7.4%
2 RASH 8,487
6.2%
3 SEIZURE 6,692
4.9%
4 NAUSEA 6,282
4.6%
5 FATIGUE 6,040
4.4%
6 OFF LABEL USE 6,014
4.4%
7 DIZZINESS 5,888
4.3%
8 HEADACHE 5,668
4.1%
9 DEPRESSION 5,066
3.7%
10 VOMITING 4,663
3.4%
11 SOMNOLENCE 4,422
3.2%
12 PYREXIA 4,402
3.2%
13 ANXIETY 4,377
3.2%
14 DRUG INTERACTION 4,365
3.2%
15 TOXICITY TO VARIOUS AGENTS 4,189
3.1%
16 INSOMNIA 3,811
2.8%
17 CONVULSION 3,675
2.7%
18 PAIN 3,659
2.7%
19 CONDITION AGGRAVATED 3,649
2.7%
20 FALL 3,641
2.7%
21 FOETAL EXPOSURE DURING PREGNANCY 3,375
2.5%
22 EPILEPSY 3,294
2.4%
23 COMPLETED SUICIDE 3,284
2.4%
24 DIARRHOEA 3,250
2.4%
25 CONFUSIONAL STATE 3,185
2.3%
26 TREMOR 3,169
2.3%
27 MALAISE 3,123
2.3%
28 WEIGHT INCREASED 3,116
2.3%
29 PRURITUS 2,961
2.2%
30 DYSPNOEA 2,887
2.1%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.