Loperamide Hydrochloride / Dimethicone

Common brands: Imodium Multi-Symptom Relief, Imodium A-D, Tylenol Extra Strength, Tylenol Regular Strength, Vitamin D

Top reporter: Kenvue Brands Llc

Nonsteroidal Anti-inflammatory Drug [EPC]Corticosteroid [EPC]Benzodiazepine [EPC]Provitamin D2 Compound [EPC]Platelet Aggregation Inhibitor [EPC]
31,490
Total Reports
11,481
Serious Reports
2,511
Death Reports
30
Reported Reactions
Death Report Ratio: High (7.97%)

Patient Demographics

Male
10,768
Female
18,275

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Loperamide Hydrochloride / Dimethicone.

# Reaction Reports % of Total
1 DIARRHOEA 6,397
14.1%
2 DRUG INEFFECTIVE 3,116
6.9%
3 NAUSEA 3,050
6.7%
4 FATIGUE 2,572
5.7%
5 OFF LABEL USE 2,233
4.9%
6 VOMITING 2,096
4.6%
7 CONSTIPATION 1,738
3.8%
8 WEIGHT DECREASED 1,502
3.3%
9 INCORRECT DOSE ADMINISTERED 1,379
3.0%
10 DYSPNOEA 1,337
2.9%
11 ABDOMINAL PAIN 1,334
2.9%
12 HEADACHE 1,326
2.9%
13 ASTHENIA 1,293
2.9%
14 DEHYDRATION 1,223
2.7%
15 DECREASED APPETITE 1,205
2.7%
16 DIZZINESS 1,190
2.6%
17 PNEUMONIA 1,165
2.6%
18 PAIN 1,103
2.4%
19 PYREXIA 1,043
2.3%
20 MALAISE 988
2.2%
21 COUGH 921
2.0%
22 ARTHRALGIA 880
1.9%
23 ABDOMINAL PAIN UPPER 873
1.9%
24 DEATH 830
1.8%
25 DYSPHAGIA 820
1.8%
26 RASH 798
1.8%
27 FALL 787
1.7%
28 PAIN IN EXTREMITY 752
1.7%
29 ANAEMIA 698
1.5%
30 CONDITION AGGRAVATED 676
1.5%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.