Pertuzumab

Common brands: Perjeta, Herceptin, Ontruzant, Herzuma, Docetaxel

Top reporter: Genentech, Inc.

HER2/neu Receptor Antagonist [EPC]Microtubule Inhibitor [EPC]Platinum-based Drug [EPC]Corticosteroid [EPC]Aromatase Inhibitor [EPC]
26,574
Total Reports
12,291
Serious Reports
2,652
Death Reports
30
Reported Reactions
Death Report Ratio: High (9.98%)

Patient Demographics

Male
694
Female
21,822

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Pertuzumab.

# Reaction Reports % of Total
1 DIARRHOEA 3,738
11.6%
2 OFF LABEL USE 2,325
7.2%
3 NAUSEA 1,918
5.9%
4 FATIGUE 1,888
5.9%
5 ALOPECIA 1,562
4.8%
6 MYELOSUPPRESSION 1,485
4.6%
7 DISEASE PROGRESSION 1,317
4.1%
8 VOMITING 1,264
3.9%
9 DYSPNOEA 1,174
3.6%
10 NEUROPATHY PERIPHERAL 1,113
3.4%
11 DEATH 1,092
3.4%
12 PYREXIA 1,053
3.3%
13 NEUTROPENIA 990
3.1%
14 RASH 923
2.9%
15 ANAEMIA 872
2.7%
16 ASTHENIA 824
2.6%
17 HEADACHE 772
2.4%
18 FEBRILE NEUTROPENIA 744
2.3%
19 EJECTION FRACTION DECREASED 707
2.2%
20 DECREASED APPETITE 691
2.1%
21 PAIN 634
2.0%
22 METASTASES TO CENTRAL NERVOUS SYSTEM 626
1.9%
23 PRURITUS 609
1.9%
24 PNEUMONIA 602
1.9%
25 NO ADVERSE EVENT 591
1.8%
26 DRUG INEFFECTIVE 571
1.8%
27 CONSTIPATION 552
1.7%
28 CHILLS 546
1.7%
29 WEIGHT DECREASED 546
1.7%
30 THROMBOCYTOPENIA 542
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.