Selexipag

Common brands: Uptravi, Opsumit, Adcirca, Letairis, Ambrisentan

Top reporter: Actelion Pharmaceuticals Us, Inc.

Prostacyclin Receptor Agonist [EPC]Endothelin Receptor Antagonist [EPC]Phosphodiesterase 5 Inhibitor [EPC]Prostacycline Vasodilator [EPC]Soluble Guanylate Cyclase Stimulator [EPC]
25,258
Total Reports
12,970
Serious Reports
4,792
Death Reports
30
Reported Reactions
Death Report Ratio: High (18.97%)

Patient Demographics

Male
6,365
Female
17,805

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Selexipag.

# Reaction Reports % of Total
1 HEADACHE 6,659
10.7%
2 DIARRHOEA 5,115
8.2%
3 DYSPNOEA 4,710
7.6%
4 NAUSEA 4,059
6.5%
5 FATIGUE 2,563
4.1%
6 DEATH 2,508
4.0%
7 PAIN IN JAW 2,406
3.9%
8 DIZZINESS 2,273
3.6%
9 PAIN 2,189
3.5%
10 PAIN IN EXTREMITY 2,100
3.4%
11 MYALGIA 1,967
3.2%
12 VOMITING 1,929
3.1%
13 PNEUMONIA 1,794
2.9%
14 MALAISE 1,785
2.9%
15 HYPOTENSION 1,703
2.7%
16 PULMONARY ARTERIAL HYPERTENSION 1,682
2.7%
17 ARTHRALGIA 1,610
2.6%
18 HOSPITALISATION 1,425
2.3%
19 DECREASED APPETITE 1,400
2.2%
20 FLUID RETENTION 1,306
2.1%
21 COUGH 1,224
2.0%
22 DYSPNOEA EXERTIONAL 1,203
1.9%
23 CONDITION AGGRAVATED 1,183
1.9%
24 FLUSHING 1,138
1.8%
25 ASTHENIA 1,134
1.8%
26 PERIPHERAL SWELLING 1,088
1.7%
27 OXYGEN SATURATION DECREASED 1,060
1.7%
28 CHEST PAIN 1,040
1.7%
29 WEIGHT DECREASED 1,034
1.7%
30 OEDEMA PERIPHERAL 1,032
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.