Zonisamide

Common brands: Zonegran, Zonisade, Keppra Xr, Keppra, Lamictal Xr

Top reporter: Advanz Pharma (Us) Corp.

Anti-epileptic Agent [EPC]Benzodiazepine [EPC]Mood Stabilizer [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Corticosteroid [EPC]
14,484
Total Reports
5,237
Serious Reports
875
Death Reports
30
Reported Reactions
Death Report Ratio: High (6.04%)

Patient Demographics

Male
4,492
Female
7,028

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Zonisamide.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 1,664
10.8%
2 SEIZURE 1,627
10.6%
3 OFF LABEL USE 908
5.9%
4 FATIGUE 708
4.6%
5 SOMNOLENCE 666
4.3%
6 CONVULSION 622
4.0%
7 DIZZINESS 570
3.7%
8 NAUSEA 564
3.7%
9 HEADACHE 551
3.6%
10 FALL 507
3.3%
11 DRUG INTERACTION 470
3.1%
12 CONDITION AGGRAVATED 454
3.0%
13 VOMITING 442
2.9%
14 DIARRHOEA 417
2.7%
15 EPILEPSY 387
2.5%
16 WEIGHT DECREASED 371
2.4%
17 DEPRESSION 366
2.4%
18 INSOMNIA 364
2.4%
19 RASH 344
2.2%
20 DECREASED APPETITE 331
2.2%
21 PYREXIA 328
2.1%
22 ANXIETY 317
2.1%
23 AGGRESSION 313
2.0%
24 PAIN 306
2.0%
25 STATUS EPILEPTICUS 306
2.0%
26 GENERALISED TONIC-CLONIC SEIZURE 299
1.9%
27 PRODUCT USE IN UNAPPROVED INDICATION 298
1.9%
28 PNEUMONIA 295
1.9%
29 PRODUCT DOSE OMISSION ISSUE 287
1.9%
30 FOETAL EXPOSURE DURING PREGNANCY 285
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.