Simvastatin

Common brands: Zocor, Ecotrin, Aspirin 325, Aspirin 81, Bayer Low Dose

Top reporter: Organon Llc

HMG-CoA Reductase Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Platelet Aggregation Inhibitor [EPC]Proton Pump Inhibitor [EPC]Loop Diuretic [EPC]
247,115
Total Reports
52,686
Serious Reports
22,054
Death Reports
30
Reported Reactions
Death Report Ratio: High (8.92%)

Patient Demographics

Male
113,852
Female
119,555

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Simvastatin.

# Reaction Reports % of Total
1 FATIGUE 13,672
5.8%
2 NAUSEA 13,026
5.5%
3 DYSPNOEA 12,506
5.3%
4 DIARRHOEA 11,884
5.0%
5 DRUG INEFFECTIVE 11,431
4.8%
6 DIZZINESS 11,036
4.7%
7 FALL 9,233
3.9%
8 ASTHENIA 9,190
3.9%
9 PAIN 9,140
3.9%
10 HEADACHE 8,880
3.8%
11 MYALGIA 8,387
3.6%
12 VOMITING 8,159
3.5%
13 MALAISE 7,643
3.2%
14 ARTHRALGIA 7,606
3.2%
15 DRUG INTERACTION 7,288
3.1%
16 PAIN IN EXTREMITY 6,988
3.0%
17 OFF LABEL USE 6,910
2.9%
18 ACUTE KIDNEY INJURY 6,536
2.8%
19 DEATH 6,402
2.7%
20 PNEUMONIA 5,945
2.5%
21 PRURITUS 5,856
2.5%
22 WEIGHT DECREASED 5,841
2.5%
23 RENAL FAILURE 5,548
2.4%
24 RHABDOMYOLYSIS 5,353
2.3%
25 COUGH 5,290
2.2%
26 RASH 5,258
2.2%
27 MYOCARDIAL INFARCTION 5,248
2.2%
28 INSOMNIA 5,246
2.2%
29 ANAEMIA 5,239
2.2%
30 CHEST PAIN 5,168
2.2%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.