Sorafenib

Common brands: Nexavar, Sorafenib Tosylate, Lasix, Acid Reducer, Aldactone

Top reporter: Bayer Healthcare Pharmaceuticals Inc.

Kinase Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Loop Diuretic [EPC]Nucleoside Metabolic Inhibitor [EPC]Proton Pump Inhibitor [EPC]
20,575
Total Reports
6,862
Serious Reports
5,070
Death Reports
30
Reported Reactions
Death Report Ratio: High (24.64%)

Patient Demographics

Male
13,353
Female
5,345

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Sorafenib.

# Reaction Reports % of Total
1 DIARRHOEA 2,951
9.3%
2 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 2,167
6.8%
3 HEPATOCELLULAR CARCINOMA 1,897
5.9%
4 FATIGUE 1,794
5.6%
5 OFF LABEL USE 1,695
5.3%
6 RASH 1,458
4.6%
7 DEATH 1,452
4.6%
8 DECREASED APPETITE 1,448
4.5%
9 NAUSEA 1,365
4.3%
10 ASTHENIA 1,186
3.7%
11 HYPERTENSION 1,148
3.6%
12 PYREXIA 1,060
3.3%
13 VOMITING 981
3.1%
14 PAIN IN EXTREMITY 965
3.0%
15 WEIGHT DECREASED 917
2.9%
16 ABDOMINAL PAIN 835
2.6%
17 ALOPECIA 774
2.4%
18 BLISTER 735
2.3%
19 DYSPNOEA 715
2.2%
20 HEPATIC FUNCTION ABNORMAL 664
2.1%
21 ASCITES 629
2.0%
22 PRURITUS 594
1.9%
23 MALAISE 590
1.9%
24 BLOOD PRESSURE INCREASED 587
1.8%
25 ANAEMIA 586
1.8%
26 PAIN 584
1.8%
27 ERYTHEMA 557
1.7%
28 HEADACHE 531
1.7%
29 CONSTIPATION 509
1.6%
30 DRY SKIN 509
1.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.