Voxelotor

Common brands: Oxbryta, Hydrea, Siklos, Droxia, Hydroxyurea

Top reporter: Global Blood Therapeutics, Inc, A Subsidiary Of Pfizer Inc.

Hemoglobin S Polymerization Inhibitor [EPC]Antimetabolite [EPC]Vitamin C [EPC]Vitamin B12 [EPC]Vitamin D [EPC]
22,291
Total Reports
17,111
Serious Reports
414
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (1.86%)

Patient Demographics

Male
8,702
Female
13,113

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Voxelotor.

# Reaction Reports % of Total
1 SICKLE CELL ANAEMIA WITH CRISIS 11,216
28.5%
2 PRODUCT DOSE OMISSION ISSUE 5,172
13.2%
3 DIARRHOEA 3,187
8.1%
4 OFF LABEL USE 2,416
6.1%
5 NAUSEA 2,016
5.1%
6 HEADACHE 1,691
4.3%
7 ABDOMINAL PAIN UPPER 1,171
3.0%
8 PAIN 1,082
2.8%
9 THERAPY CESSATION 1,040
2.6%
10 FATIGUE 1,007
2.6%
11 ABDOMINAL DISCOMFORT 969
2.5%
12 THERAPY INTERRUPTED 900
2.3%
13 VOMITING 833
2.1%
14 HAEMOGLOBIN DECREASED 752
1.9%
15 ABDOMINAL PAIN 627
1.6%
16 RASH 574
1.5%
17 MALAISE 535
1.4%
18 PNEUMONIA 431
1.1%
19 ACUTE CHEST SYNDROME 391
1.0%
20 PYREXIA 367
0.9%
21 DIZZINESS 362
0.9%
22 DEATH 331
0.8%
23 HOSPITALISATION 307
0.8%
24 PRODUCT USE COMPLAINT 298
0.8%
25 THERAPY NON-RESPONDER 295
0.8%
26 INTENTIONAL PRODUCT MISUSE 277
0.7%
27 COVID-19 271
0.7%
28 PAIN IN EXTREMITY 264
0.7%
29 PRURITUS 264
0.7%
30 WEIGHT DECREASED 251
0.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.